Food-dependent exercise-induced anaphylaxis

BMJ Case Rep. 2018 Apr 11:2018:bcr2017222370. doi: 10.1136/bcr-2017-222370.

Abstract

Food-dependent exercise-induced anaphylaxis (FDEIAn), first reported in 1979, is a condition defined by the consumption of a trigger food with temporally related exercise that results in an immediate hypersensitivity (type 1) reaction in the setting of the trigger food being tolerated independent of exercise and exercise being tolerated in the absence of trigger food consumption. The most common trigger food in the west is wheat and shellfish in Asia. The exact mechanism of FDEIAn is unknown, though several hypotheses exist. Cofactors such as non-steroidal anti-inflammatory drug use, alcohol consumption and others have been associated with reported cases.

Keywords: allergy; asthma; general practice / family medicine; immunology.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Allergens / adverse effects
  • Anaphylaxis / diagnosis
  • Anaphylaxis / etiology*
  • Dancing*
  • Exercise
  • Female
  • Food Hypersensitivity / complications*
  • Humans
  • Urticaria / etiology*

Substances

  • Allergens