Subclinical meningoventriculitis as a cause of obstructive hydrocephalus

BMJ Case Rep. 2017 Oct 11:2017:bcr2017221849. doi: 10.1136/bcr-2017-221849.

Abstract

Communicating hydrocephalus may complicate infantile bacterial meningitis, typically presenting with systemic features of infection. We report a rare case of 'subclinical meningoventriculitis' causing obstructive hydrocephalus and its challenging management. A healthy 10-week-old immunocompetent male patient presented with failure to thrive and vomiting, secondary to presumed gastro-oesophageal reflux. The child was neurologically alert, afebrile with normal inflammatory markers. Progressive macrocephaly prompted an MRI confirming triventricular hydrocephalus secondary to aqueductal stenosis. An endoscopic third ventriculostomy was performed however abandoned intraoperatively due to the unexpected finding of intraventricular purulent cerebrospinal fluid. A 6-week course of intravenous ceftriaxone was commenced for Escherichia coli meningoventriculitis. However, the child was readmitted 18 days postoperatively with acute hydrocephalus requiring a ventricular washout and staged ventriculoperitoneal shunt insertion at 4 weeks. Serial head circumference measurements are paramount in the assessment of a paediatric patient. In an immunocompetent child, a subclinical fibropurulent meningoventriculitis can result in several management challenges.

Keywords: failure to thrive; hydrocephalus; infant health; infection (neurology); meningitis.

Publication types

  • Case Reports

MeSH terms

  • Amoxicillin / therapeutic use
  • Anti-Bacterial Agents / therapeutic use*
  • Ceftriaxone / therapeutic use*
  • Cerebral Ventriculitis / complications
  • Cerebral Ventriculitis / microbiology*
  • Cerebral Ventriculitis / therapy
  • Cerebrospinal Fluid Shunts
  • Humans
  • Hydrocephalus / etiology
  • Hydrocephalus / microbiology*
  • Hydrocephalus / therapy
  • Infant, Newborn
  • Injections
  • Male
  • Meningoencephalitis / complications
  • Meningoencephalitis / microbiology*
  • Meningoencephalitis / therapy
  • Polytetrafluoroethylene / therapeutic use*
  • Treatment Outcome
  • Ureter
  • Urinary Tract Infections / therapy*
  • Ventriculostomy

Substances

  • Anti-Bacterial Agents
  • Ceftriaxone
  • Amoxicillin
  • Polytetrafluoroethylene