Mitral valve vegetation diagnosed with oesophageal ultrasound with bronchoscope (EUS-B)

BMJ Case Rep. 2017 May 15:2017:bcr2016218849. doi: 10.1136/bcr-2016-218849.

Abstract

Oesophageal ultrasound with bronchoscope (EUS-B) is designed to evaluate mediastinal structures. We describe a case of a 78-year-old woman who presented with altered mental status for 2 weeks. CT head revealed a subacute infarct in the right middle cerebral artery distribution. She was also found to have a lung mass on chest imaging. EUS-B-guided fine needle aspiration demonstrated the presence of adenocarcinoma in station 7 lymph node and in the mass. Immunohistochemistry confirmed it to be a lung primary as the Thyroid Transcription Factor-1 (TTF-1) was strongly positive. During the procedure, the cardiac valves were evaluated, and a mitral valve vegetation was noted. Formal echocardiography confirmed the presence of the vegetation. During hospital stay, the patient developed fever. Her blood cultures grew oxacillin-resistant Staphylococcus aureus. She was subsequently treated for infective endocarditis. We suggest that the use of EUS-B to routinely scan adjacent structures during a procedure may help obtain additional clinical information that may be critical to patient management.

Keywords: Adult intensive care; Cancer intervention; Geriatric medicine; Valvar diseases.

Publication types

  • Case Reports

MeSH terms

  • Adenocarcinoma / immunology
  • Adenocarcinoma / pathology
  • Adenocarcinoma of Lung
  • Administration, Intravenous
  • Aged
  • Anti-Bacterial Agents / therapeutic use
  • Biopsy, Fine-Needle / methods
  • Bronchoscopy / methods*
  • Confusion / diagnostic imaging*
  • Confusion / etiology
  • Diagnosis, Differential
  • Echocardiography
  • Endocarditis, Bacterial / drug therapy*
  • Endocarditis, Bacterial / microbiology
  • Esophagus / diagnostic imaging*
  • Female
  • Humans
  • Lung Neoplasms / immunology
  • Lung Neoplasms / pathology
  • Lymph Nodes / pathology
  • Middle Cerebral Artery / diagnostic imaging
  • Middle Cerebral Artery / pathology*
  • Mitral Valve / diagnostic imaging*
  • Mitral Valve / pathology
  • Staphylococcus aureus / growth & development
  • Staphylococcus aureus / isolation & purification
  • Thyroid Nuclear Factor 1 / metabolism
  • Tomography, X-Ray Computed / methods
  • Treatment Outcome
  • Ultrasonography / methods*
  • Vancomycin / administration & dosage
  • Vancomycin / therapeutic use

Substances

  • Anti-Bacterial Agents
  • NKX2-1 protein, human
  • Thyroid Nuclear Factor 1
  • Vancomycin