Maternal bradycardia occurring prior to onset of HELLP syndrome in a woman with pre-eclampsia

BMJ Case Rep. 2017 May 13:2017:bcr2016217964. doi: 10.1136/bcr-2016-217964.

Abstract

A 36-year-old nulliparous woman developed pre-eclampsia at gestational week (GW) 28-6/7 Cardiac status was checked regularly. Heart rate of 93 beats per minute (bpm) with left atrial diameter (LAD) of 35 mm, left ventricular hypertrophy and inferior vena cava diameter (IVCD) of 8 mm at GW 32-0/7 decreased to 48 bpm with an expanded IVCD to 25 mm, dilated left atrium (LAD to 39 mm), increased pulmonary arterial pressure, increased systemic vascular resistance (approximate 3000 dyn s/cm5) and biphasic intrarenal venous flow pattern 3.5 hours prior to childbirth at GW 32-3/7 Epigastralgia, tachycardia (160 bpm) and marked hypertension (201/111 mm Hg) occurring 2 hours after echocardiography necessitated caesarean section, with subsequent development of HELLP syndrome. Acute fluid shift from the splanchnic vasculature to central vasculature may have occurred causing HELLP syndrome as a result from vasospasm associated with sympathetic hyperactivity. The cause of bradycardia prior to tachycardia remains unclear.

Keywords: Cardiovascular medicine; Obstetrics and gynaecology.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Bradycardia / diagnosis
  • Bradycardia / etiology*
  • Bradycardia / physiopathology
  • Cesarean Section / methods
  • Echocardiography / methods
  • Female
  • HELLP Syndrome / diagnosis*
  • HELLP Syndrome / physiopathology
  • HELLP Syndrome / therapy
  • Heart Rate / physiology
  • Humans
  • Hypertension / complications*
  • Hypertension / physiopathology
  • Hypertrophy, Left Ventricular / diagnostic imaging
  • Japan / epidemiology
  • Pre-Eclampsia / diagnosis*
  • Pre-Eclampsia / physiopathology
  • Pre-Eclampsia / surgery
  • Pregnancy
  • Sympathetic Nervous System / physiopathology*
  • Tachycardia / diagnosis
  • Tachycardia / etiology*
  • Tachycardia / physiopathology
  • Treatment Outcome
  • Vena Cava, Inferior / diagnostic imaging