Atypical presentation of anti-GBM nephritis in a 90-year-old patient

BMJ Case Rep. 2016 Nov 29:2016:bcr2016217990. doi: 10.1136/bcr-2016-217990.

Abstract

A 90-year-old woman who had bloody diarrhoea, nausea, weakness and reduced urine output was found to have acute kidney injury. Her inflammatory markers were raised and her chest X-ray suggested an inflammatory process. She was initially suspected to have acute kidney injury secondary to dehydration and sepsis but when her autoimmune screen returned positive for antiglomerular basement membrane antibodies our diagnosis and management strategy was reconsidered. This is a case report of Goodpasture disease presenting in an elderly patient.

Publication types

  • Case Reports

MeSH terms

  • Acute Kidney Injury / diagnosis*
  • Aged, 80 and over
  • Albuterol / therapeutic use*
  • Anti-Bacterial Agents / administration & dosage
  • Anti-Glomerular Basement Membrane Disease / diagnosis*
  • Anti-Glomerular Basement Membrane Disease / physiopathology
  • Anti-Glomerular Basement Membrane Disease / therapy
  • Bronchodilator Agents / therapeutic use*
  • Ceftriaxone / administration & dosage
  • Diarrhea / etiology
  • Esomeprazole / administration & dosage
  • Fatal Outcome
  • Female
  • Humans
  • Nausea / etiology
  • Palliative Care*
  • Patient Comfort
  • Plasma Exchange*
  • Proton Pump Inhibitors / administration & dosage

Substances

  • Anti-Bacterial Agents
  • Bronchodilator Agents
  • Proton Pump Inhibitors
  • Ceftriaxone
  • Esomeprazole
  • Albuterol