Oh rats! Fever, rash and arthritis in a young woman

BMJ Case Rep. 2015 Dec 23:2015:bcr2015212240. doi: 10.1136/bcr-2015-212240.

Abstract

A 17-year-old girl presented with worsening right-sided hip and low back pain for 2 days. She had also experienced intermittent fevers and a recurring maculopapular rash over the past 2 weeks. Social history revealed the presence of three domestic rats living in the girl's home. Blood cultures returned positive for Streptobacillus moniliformis, the causative agent of rat-bite fever. Rat-bite fever often goes undiagnosed, as the clinical presentation is non-specific. Untreated, the infection can result in death due to sepsis or endocarditis. The bacterium is generally susceptible to penicillin antibiotics with full clinical recovery when treated in a timely and appropriate manner. After 4 weeks of intravenous antibiotics, our patient fully recovered without long-term sequelae.

Publication types

  • Case Reports

MeSH terms

  • Adolescent
  • Animals
  • Arthritis, Infectious / diagnosis*
  • Arthritis, Infectious / etiology
  • Bites and Stings / complications
  • Bites and Stings / microbiology*
  • Environment
  • Exanthema / diagnosis*
  • Exanthema / etiology
  • Female
  • Fever / diagnosis*
  • Fever / etiology
  • Humans
  • Penicillins / therapeutic use*
  • Rat-Bite Fever / diagnosis*
  • Rat-Bite Fever / drug therapy
  • Rat-Bite Fever / etiology
  • Rat-Bite Fever / microbiology
  • Rats
  • Streptobacillus / growth & development*
  • Zoonoses / diagnosis
  • Zoonoses / drug therapy
  • Zoonoses / microbiology

Substances

  • Penicillins