Invasive pulmonary aspergillosis in a patient presenting with idiopathic systemic capillary leak syndrome

BMJ Case Rep. 2014 May 23:2014:bcr2014203764. doi: 10.1136/bcr-2014-203764.

Abstract

A 54-year-old man presented to our emergency department with fever and dyspnoea. He required vigorous haemodynamic support and mechanical ventilation for hypotensive distributive shock with hypoalbuminaemia, haemoconcentration, rhabdomyolysis and acute renal failure, consistent with idiopathic systemic capillary leak syndrome. Left lung consolidation and hypoxaemia were observed 6 days after admission. Sputum smear revealed the presence of acute angled branching hyphae, consistent with a diagnosis of invasive pulmonary aspergillosis. Antifungal therapy was administered and mechanical ventilation discontinued on day 66. The patient recovered and was discharged from the hospital on day 185.

Publication types

  • Case Reports

MeSH terms

  • Antifungal Agents / therapeutic use*
  • Capillary Leak Syndrome / complications
  • Capillary Leak Syndrome / immunology
  • Capillary Leak Syndrome / therapy*
  • Humans
  • Invasive Pulmonary Aspergillosis / complications
  • Invasive Pulmonary Aspergillosis / drug therapy*
  • Invasive Pulmonary Aspergillosis / immunology
  • Lung / diagnostic imaging*
  • Male
  • Middle Aged
  • Opportunistic Infections / complications
  • Opportunistic Infections / drug therapy*
  • Opportunistic Infections / immunology
  • Radiography

Substances

  • Antifungal Agents