Unusual case of subarachnoid haemorrhage in patient with Fabry's disease: case report and literature review

BMJ Case Rep. 2012 Jul 3:2012:bcr0220125727. doi: 10.1136/bcr.02.2012.5727.

Abstract

Fabry's disease is a rare, X linked recessive disease affecting 1 in 40 000 persons. The symptoms result from a lack of or a non-functioning enzyme α galactosidase, which leads to globotriaosylceramide accumulation in the walls of blood vessels. Mortality is generally from cardiac or renal complications and death from subarachnoid haemorrhage is distinctly rare. The authors report a man with Fabry's disease who died after subarachnoid haemorrhage from a progressively enlarging fusiform basilar aneurysm.

Publication types

  • Case Reports

MeSH terms

  • Basilar Artery*
  • Fabry Disease / complications*
  • Fatal Outcome
  • Humans
  • Intracranial Aneurysm / diagnosis
  • Intracranial Aneurysm / etiology*
  • Magnetic Resonance Imaging
  • Male
  • Subarachnoid Hemorrhage / etiology*