Hepatitis B virus related membranous glomerulonephritis and proteinuria treated with lamivudine and tenofovir

BMJ Case Rep. 2011 Aug 31:2011:bcr0520114287. doi: 10.1136/bcr.05.2011.4287.

Abstract

Membranous glomerulonephritis is the most common histological renal lesion associated with hepatitis B virus (HBV) infection. The authors describe here a case of a patient presenting with the nephrotic syndrome and HBV infection but without progressive liver disease. The use of lamivudine and tenofovir resulted in arrest of proteinuria and stabilisation of renal function.

Publication types

  • Case Reports

MeSH terms

  • Adenine / analogs & derivatives*
  • Adenine / therapeutic use
  • Glomerulonephritis, Membranous / drug therapy*
  • Glomerulonephritis, Membranous / virology*
  • Hepatitis B, Chronic / complications*
  • Hepatitis B, Chronic / drug therapy*
  • Humans
  • Lamivudine / therapeutic use*
  • Male
  • Organophosphonates / therapeutic use*
  • Proteinuria / drug therapy*
  • Proteinuria / virology*
  • Reverse Transcriptase Inhibitors / therapeutic use*
  • Tenofovir
  • Young Adult

Substances

  • Organophosphonates
  • Reverse Transcriptase Inhibitors
  • Lamivudine
  • Tenofovir
  • Adenine