Intravenous (IV) drug abuse is a common problem in our society. One complication of this practice is venous stenosis, endovascular management of which can be technically challenging especially in patients with a hostile groin. We describe an ipsilateral retrograde popliteal approach in a 26-year-old IV drug user presenting with swelling of the left leg secondary to common femoral vein stenosis. This approach represents the next best method following failed contralateral/cross-bifurcation access and is a safe, convenient alternative offering a "straight run" at the lesion.