Successful treatment of primary cardiac lymphoma with atrioventricular nodal block

Int Heart J. 2005 Sep;46(5):927-31. doi: 10.1536/ihj.46.927.

Abstract

A 69-year-old female suffering from third-degree atrioventricular block with syncope underwent permanent pacemaker implantation. However, she developed shortness of breath 2 months after the implantation. Blood tests revealed elevated levels of LDH, CRP, BNP, and SIL-2R. Transthoracic echocardiography showed thickened left and right atrial walls with mild pericardial effusion. A diagnosis was made based on a CT scan and histology. Although most primary cardiac malignant lymphomas are associated with a poor prognosis, the patient was treated successfully with chemotherapy.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Antineoplastic Combined Chemotherapy Protocols / administration & dosage
  • Antineoplastic Combined Chemotherapy Protocols / therapeutic use*
  • Cyclophosphamide / administration & dosage
  • Doxorubicin / administration & dosage
  • Drug Administration Schedule
  • Female
  • Heart Block / complications*
  • Heart Block / therapy
  • Heart Neoplasms / drug therapy*
  • Heart Neoplasms / etiology
  • Humans
  • Lymphoma, B-Cell / drug therapy*
  • Lymphoma, B-Cell / etiology
  • Lymphoma, Large B-Cell, Diffuse / drug therapy*
  • Lymphoma, Large B-Cell, Diffuse / etiology
  • Pacemaker, Artificial
  • Prednisolone / administration & dosage
  • Vincristine / administration & dosage

Substances

  • Vincristine
  • Doxorubicin
  • Cyclophosphamide
  • Prednisolone

Supplementary concepts

  • VAP-cyclo protocol