Abstract
The case of a 66-year-old woman with rapidly progressive respiratory distress caused by a massive anterior neck mass with tracheal compression is presented. Within 24 hours, fine-needle aspiration cytology (FNAC) and immunocytochemistry provided a diagnosis of high-grade B-cell lymphoma and the opportunity to institute a chemotherapeutic regimen resulting in a rapid volume reduction and airway expansion. One year after combined modality treatment the patient was in complete remission (with an estimated thyroid volume of 4 cm3). This case report illustrates the advantages of FNAC and immunocytochemistry in the diagnosis of thyroid lymphoma.
MeSH terms
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Aged
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Antineoplastic Combined Chemotherapy Protocols / therapeutic use
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Biopsy, Needle
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Combined Modality Therapy
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Cyclophosphamide / therapeutic use
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Doxorubicin / therapeutic use
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Female
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Follow-Up Studies
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Humans
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Immunohistochemistry
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Laryngoscopy
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Lymphoma, B-Cell / diagnostic imaging
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Lymphoma, B-Cell / drug therapy
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Lymphoma, B-Cell / pathology*
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Lymphoma, B-Cell / radiotherapy
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Lymphoma, Large B-Cell, Diffuse / diagnostic imaging
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Lymphoma, Large B-Cell, Diffuse / drug therapy
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Lymphoma, Large B-Cell, Diffuse / pathology*
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Lymphoma, Large B-Cell, Diffuse / radiotherapy
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Neoplasm Staging
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Prednisone / therapeutic use
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Thyroid Neoplasms / diagnostic imaging
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Thyroid Neoplasms / drug therapy
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Thyroid Neoplasms / pathology*
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Thyroid Neoplasms / radiotherapy
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Tomography, X-Ray Computed
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Vincristine / therapeutic use
Substances
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Vincristine
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Doxorubicin
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Cyclophosphamide
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Prednisone