Progressive gastrointestinal histoplasmosis leading to colonic obstruction two years after initial presentation

Am J Gastroenterol. 2001 Jan;96(1):221-2. doi: 10.1111/j.1572-0241.2001.03479.x.

Abstract

A 37-yr-old man from Ecuador presented with abdominal pain, diarrhea, and weight loss. Endoscopy revealed duodenal histoplasmosis. The patient improved with antifungal therapy but was readmitted 2 yr later with diarrhea and fever. Colonoscopy revealed histoplasmosis lesions, including a constricting transverse colon lesion. The patient refused surgery and died of colonic perforation. We discuss the diagnosis and management of gastrointestinal histoplasmosis in this report.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Colonic Diseases / diagnosis*
  • Colonic Diseases / etiology
  • Colonic Diseases / surgery
  • Colonoscopy
  • Disease Progression
  • Fatal Outcome
  • Gastrointestinal Diseases / complications
  • Gastrointestinal Diseases / diagnosis
  • Gastrointestinal Diseases / surgery
  • Histoplasmosis / complications
  • Histoplasmosis / diagnosis*
  • Histoplasmosis / surgery
  • Humans
  • Intestinal Obstruction / diagnosis*
  • Intestinal Obstruction / etiology
  • Intestinal Obstruction / surgery
  • Intestinal Perforation / diagnosis*
  • Intestinal Perforation / etiology
  • Intestinal Perforation / surgery
  • Male
  • Treatment Refusal