Case ReportsAmeloblastic carcinoma: Report of an aggressive case with multiple bony metastases*
Section snippets
Case report
A 22-year-old white man presented to his dental practitioner in June 1993 with discomfort in the area of his right mandibular second and third molar teeth. After removal of the teeth, an abnormal tissue was detected in the extraction socket. He was then referred to Roswell Park Cancer Institute for further management. Physical examination revealed a healing mandibular extraction socket. There was a diffuse, nontender swelling of the buccal sulcus of the mandible adjacent to the second and third
Discussion
The typical intraosseous ameloblastoma is a low-grade malignancy, which has the tendency to infiltrate cancellous bone without causing bone resorption. Although the clinical course is characterized by local recurrences, rarely do these tumors metastasize and are generally considered benign. Of a total of 126 patients treated at the Mayo Clinic, only 15 died as a result of the tumor.8 Death from ameloblastoma is usually seen in cases with uncontrolled local growth and involvement of vital
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Cited by (56)
A case of maxillary ameloblastic carcinoma with atypical histology
2021, Journal of Oral and Maxillofacial Surgery, Medicine, and PathologyOdontogenic Cysts and Tumors
2020, Gnepp's Diagnostic Surgical Pathology of the Head and Neck, Third EditionHuge ameloblastic carcinoma of the mandible with metastases treated in several different ways
2019, British Journal of Oral and Maxillofacial SurgeryReconnoitre ameloblastic carcinoma: A prognostic update
2018, Oral OncologyAmeloblastic carcinoma (secondary type) with extensive squamous differentiation areas and dedifferentiated regions
2016, Oral Surgery, Oral Medicine, Oral Pathology and Oral RadiologyCitation Excerpt :Recurrences are often described and seem to be mainly related to the treatment modality used, ranging from 28.3% in more aggressive approaches to more than 92.3% after conservative managements.8,13 Distant metastases are not infrequent, occurring as early or late events, usually involving the lungs, brain, liver, and bone.17-20 Similarly, cervical lymph node dissemination may also occur,19,21 and the 5-year survival rate ranges from 68.7% to 72.9%.7,8
Ameloblastic carcinoma: A systematic review
2024, Journal of Oral Pathology and Medicine
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Address correspondence to: Wesley L. Hicks Jr, MD, Department of Head and Neck, Roswell Park Cancer Institute, Elm and Carlton Streets, Buffalo, NY 14263. E-mail: wesley.hicks@roswell park.org.