Letter to the EditorAcute myocardial infarction with normal coronary arteries in a young man with the Behcet's disease
Introduction
Coronary artery disease is one of the most common causes of acute myocardial infarction [1]. In addition to atherosclerosis, coronary vasculitis may also cause the acute coronary syndromes [2], [3], [4]. One of the most common characteristics of Behcet's disease (BD) is vasculitis, which rarely involves the coronary arteries [5], [6], [7]. But data about clinical significance of coronary artery involvement is very limited. In Behcet's disease, acute myocardial infarction is a serious complication and an important clinical manifestation of coronary arteritis. Myocardial infarction due to coronary vasculitis in Behcet's disease is infrequent and documented in only a few cases in literature [2], [3], [4]. In this paper, we report a patient with Behcet's disease presenting acute myocardial infarction due to coronary vasculitis with normal coronary arteries.
Section snippets
Case
A 34-year-old male patient presented with chest pain located on epigastrium and retrosternal lasting for 2 h admitted to emergency department. Detailed past medical history revealed that he has no risk factors for coronary artery disease, and he had had been diagnosed as BD 7 years ago. He has not been taking medication for BD. On first examination in emergency department, blood pressure was 130/70 mm Hg and heart rate was 85 bpm. He was pale and sweated in appearance. On his chest
Discussion
Vascular involvement is the well-known characteristic of BD. It can occur even in young patients with no vascular risk factor. Especially, arterial involvement is expressed by thrombosis, stenosis, and/or aneurysms, as shown in early studies [2], [3], [4], [5], [6], [7]. The thrombosis associated with BD may be due to vascular endothelial cellular dysfunction and/or a reduction of systemic fibrinolytic activity and a rise in fibrinogen and factor VIII, but the precise mechanism of thrombosis is
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