Letter to the EditorSuppression by propranolol and amiodarone of an electrical storm refractory to metoprolol and amiodarone
Section snippets
Case report
A 60-year-old man suffering from CHF secondary to ischemic heart disease with a left ventricular ejection fraction of 18%, was admitted to the hospital for treatment of multiple episodes of ventricular tachyarrhythmias at rates between 160 and 200 bpm, 1 month after the implantation of a cardioverter–defibrillator, model Photon DR, V-230 HV (St. Jude Medical, Minneapolis, MN).
The intravenous administration of lidocaine (4 mg/min) and amiodarone (40 mg/h) for 4 days, suppressed the most rapid
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Esmolol in the management of pre-hospital refractory ventricular fibrillation: A systematic review and meta-analysis
2020, American Journal of Emergency MedicineCitation Excerpt :However, there has never been great evidence for the practice. There have been many studies looking at other β-blockers over the past decades for cardiac arrest, but these studies were done either in animals [47-54] or were single cases published many years ago [55-62], except for one in-hospital study that evaluated the ultra-short-acting β1-selective blocker landiolol, which shares similarities to esmolol, such as the metabolism pathway; however, landiolol presents faster pharmacokinetics, acts with higher potency, and have higher cardioselectivity [63]. In 2000 a non-randomized in-hospital single-center study included 49 patients who had electrical storm (ES) associated with recent myocardial infarction.
Management of monomorphic ventricular tachycardia electrical storm in structural heart disease
2019, Journal of the Saudi Heart AssociationPropranolol Versus Metoprolol for Treatment of Electrical Storm in Patients With Implantable Cardioverter-Defibrillator
2018, Journal of the American College of CardiologyPrevalence and Prognostic Significance of Nonsustained Ventricular Tachycardia in Patients With a Left Ventricular Ejection Fraction from 35% to 50%
2018, American Journal of CardiologyCitation Excerpt :Subgroup analysis demonstrated that patients taking cardioselective β blockers were less likely to have NSVT. Previous studies have demonstrated a large class effect of β blockers for suppression of ventricular ectopy, but usually nonselective β blockers show an increased efficacy compared with cardioselective β blockers.19,25 The difference in our study is likely due to underpowering of patients on nonselective β blockers.
Electrical storm and incessant ventricular tachycardia
2018, Cardiac Intensive CareManagement of electrical storm: The mechanism matters
2014, Journal of ArrhythmiaCitation Excerpt :Beta-blockers that suppress DADs by alleviating intracellular Ca2+ overload rank foremost for this purpose. It should be noted that not all beta-blockers offer the same level of antiarrhythmic effects [36], which might depend on beta-1 selectivity, a lipophilic nature, or other pleiotropic effects. Recent experimental studies have shown that carvedilol inhibits DADs by a direct action on ryanodine receptor type 2 (RyR2) independent of its beta-blocking effect [37].