Case Report
Successful surgical treatment of a primary liver gastrinoma during pregnancy: A case report

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Abstract

Primary neuroendocrine tumors of the liver, particularly gastrinomas, are exceptionally rare. We present a case of a sporadic primary liver gastrinoma in a young woman in whom the definitive diagnosis was reached, and surgical therapy was performed during pregnancy.

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Case report

A 29-year-old woman was referred to the Department of Gastroenterology of the Soroka University Medical Center in June 2000 complaining of increasingly severe and recurrent diffuse abdominal pain, chronic diarrhea, and moderate weight loss over the 3-year period before admission. Two months before, the patient had been operated on urgently because of an acute surgical abdomen resulting from a “spontaneous” perforation of the jejunum. Her family history was unremarkable. The work-up included a

Comment

There are only isolated reports of PLG, probably arising from neuroendocrine-like cells within the intrahepatic biliary tree,1., 2. with scant information in the medical literature on the management of ZES during pregnancy, without mention to a definitive surgery approach during gestation.3 We report a unique case of liver gastrinoma with typical clinical features of ZES, such as recurrent abdominal pain, chronic diarrhea, and weight loss in a pregnant patient. The results of the extensive

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