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Findings that shed new light on the possible pathogenesis of a disease or an adverse effect
CASE REPORT
Coronary artery ectasia in Crohn’s disease
  1. Theofanis Korovesis1,
  2. George Katritsis2,
  3. Panagiotis Koudounis3,
  4. Theodoros Zografos4
  1. 1First Faculty of Medicine, Charles University, Glyfada, Greece
  2. 2Department of Cardiology, Imperial College London, London, UK
  3. 3Department of Cardiology, Athens Red Cross Hospital, Athens, Greece
  4. 4Third Department of Cardiology, Hygeia Hospital, Athens, Attica, Greece
  1. Correspondence to Dr Theodoros Zografos, theodoroszografos{at}gmail.com

Summary

Coronary artery ectasia (CAE) can be ascribed, in the majority of cases, to coronary atherosclerosis. Nevertheless, the presence of isolated ectatic lesions without obstructive coronary artery disease and the association of CAE with several autoimmune diseases characterised by systemic vascular involvement suggest that the pathogenesis of CAE may extend beyond coronary atherosclerosis. We herein report the case of a 56-year-old male patient with Crohn’s disease and isolated CAE, who has been found positive for IgM and IgA antiendothelial cell antibodies, and discuss a potential pathogenic mechanism.

  • interventional cardiology
  • Crohn’s disease

https://doi.org/10.1136/bcr-2018-226813

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    Footnotes

    • Contributors TK and GDK drafted the manuscript and performed the literature review. PK and TZ had the original idea and performed the relevant biochemical determinations. TZ critically reviewed the manuscript. All authors have equally contributed to the manuscript.

    • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

    • Competing interests None declared.

    • Patient consent Obtained.

    • Provenance and peer review Not commissioned; externally peer reviewed.