BMJ Case Reports 2018; doi:10.1136/bcr-2018-225841
  • Novel treatment (new drug/intervention; established drug/procedure in new situation)

Cryoablation: a potential treatment option for renal metastasis from lung cancer?

  1. Ole Graumann3
  1. 1Radiology Department, Odense University Hospital, Odense, Denmark
  2. 2Respiratory Department, Odense University Hospital, Odense, Denmark
  3. 3Research Unit at the Department of Radiology, Institute of Clinical Research, University of Southern Denmark, Odense, Denmark
  1. Correspondence to Dr Ole Graumann, ograumann{at}
  • Accepted 22 October 2018
  • Published 1 November 2018


Cryoablation is successfully performed as a treatment for small renal cancers. The occurrence of a solitary renal metastasis from lung cancer is an uncommon finding entailing a limited knowledge on the choice of its optimal treatment. We present two patients diagnosed with non-small cell lung cancer, who were initially treated with curatively intended chemoradiotherapy. In the follow-up period, a non-symptomatic solitary renal metastasis was found in both patients. Both received CT-guided cryoablation of their renal metastases. One patient was successfully treated with no relapse, whereas the other patient received re-cryoablation due to development of a new renal metastasis. In both patients, no residual tumour was found at the 3 months’ follow-up examination. Whether the minimally invasive procedure of cryoablation is a feasible treatment in the management of solitary renal metastases from lung cancer is still undetermined. The recurrence and incomplete treatment are concerns requiring further research.


  • Contributors Study concepts: SD, OG and JRD. Study design: OG. Data acquisition: SD, OG and JRD. Quality control of data and algorithms: SD, OG and JRD. Data analysis and interpretation: SD, OG and JRD. Manuscript preparation: SD, OG and JRD. Manuscript editing: SD, OG and JRD. Manuscript review: SD, OG and JRD.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Patient consent Obtained.

  • Provenance and peer review Not commissioned; externally peer reviewed.

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