BMJ Case Reports 2018; doi:10.1136/bcr-2018-225365
  • Unusual presentation of more common disease/injury

Primary cardiac angiosarcoma: a rare cause of diffuse alveolar haemorrhage

  1. Eric Gottesman3
  1. 1Internal Medicine, Hartford HealthCare, Hartford, Connecticut, USA
  2. 2Internal Medicine, Rutgers New Jersey Medical School, Newark, New Jersey, USA
  3. 3Internal Medicine, Northwell Health, Great Neck, New York, USA
  1. Correspondence to Dr Ankit Gupta, ankitguptapulmonary{at}
  • Accepted 21 May 2018
  • Published 4 June 2018


Primary cardiac angiosarcoma is a rare disease with a dismal prognosis. We report a case of a 50-year-old man who presented with haemoptysis, cough and worsening dyspnoea. An intracardiac mass was visualised on echocardiogram. He was treated for diffuse alveolar haemorrhage and acute respiratory distress syndrome but died from refractory hypoxaemic respiratory failure leading to cardiac arrest. The diagnosis of primary cardiac angiosarcoma with haemorrhagic pulmonary metastases leading to diffuse alveolar damage was confirmed on autopsy.


  • Contributors AVP, YG and EG were involved in patient care and reviewing the manuscript. AVP and AG were involved in writing the manuscript and literature review.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Patient consent Guardian consent obtained.

  • Provenance and peer review Not commissioned; externally peer reviewed.

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