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CASE REPORT
Campylobacter fetus spondylodiscitis in a patient with HIV infection and restored CD4 count
  1. Dorien Laenens1,
  2. Mark Plazier2,3,
  3. Jeroen C H van der Hilst1,4,
  4. Peter Messiaen1,4
  1. 1Department of Infectious Diseases and Immunity, Jessa Ziekenhuis vwz, Hasselt, Belgium
  2. 2Department of Neurosurgery, Jessa Ziekenhuis vwz, Hasselt, Belgium
  3. 3Department of Morphology, Faculty of Medicine and Health Sciences, Universiteit Hasselt, Hasselt, Belgium
  4. 4BIOMED Research Institute, Universiteit Hasselt, Hasselt, Belgium
  1. Correspondence to Dr Peter Messiaen, peter.messiaen{at}jessazh.be

Summary

Campylobacter fetus (C. fetus) is a rare condition and mostly seen in elderly or immunocompromised patients. We present the first case of C. fetus spondylodiscitis in a virologically suppressed HIV seropositive patient with low back pain. MRI was performed and showed spondylodiscitis of the L4–L5 region. Empirical antibiotic therapy with flucloxacillin was started after blood cultures were drawn and an image-guided disc biopsy was performed. Blood cultures remained negative. The anaerobic culture of the puncture biopsy of the disc revealed presence of C. fetus after which the antibiotic treatment was switched to ceftriaxone. Guided by the susceptibility results, the therapy was switched to ciprofloxacin orally for 6 weeks after which the patient made full clinical, biochemical and radiographic recovery. Since no other immune-deficient conditions were noted, it is important to highlight that patients with HIV infection with restored CD4 counts and complete virological suppression can still be susceptible for infections caused by rare pathogens. Low back pain should raise suspicion for these conditions and should be examined properly.

  • bone and joint Infections
  • Hiv / Aids

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Footnotes

  • Contributors DL: first author, wrote manuscript, managed patient care. MP: wrote and revised manuscript, managed patient care. JCHvdH: wrote and revised manuscript. PM: last Author, wrote and revised manuscript, managed patient care.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Patient consent Obtained.

  • Provenance and peer review Not commissioned; externally peer reviewed.