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Summary
We report the case of a 74-year-old man with a giant cell tumour (GCT) of the right maxilla and pterygoid process. The patient presented to the maxillofacial and head and neck surgery clinic with an ulcerated lesion of the hard palate. Initial workup with CT revealed a mass within the right maxillary sinus and pterygoid process with associated bone expansion and erosion. Biopsy showed a GCT with mucosal ulceration. Two years after surgical resection, a follow-up CT revealed tumour recurrence involving the right pterygoid process and lateral pterygoid muscle. The patient was then proposed for therapy with denosumab. Under denosumab treatment, the lesion maintained stable dimensions and became sclerotic and heavily ossified.
- drugs and medicines
- head and neck cancer
- radiology
- head and neck surgery
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Footnotes
Contributors All authors contributed to the organisation and writing of the present manuscript. AB: planned, reviewed and organised the structure of this paper. DR: wrote the paper and gathered data concerning the clinical history and follow-up of the patient, as well as acquisition of previous imaging examinations. RBD: reviewed the imaging and pathology examinations available at our institution, and selected the most representative ones, and performed comparative retrospective examinations as well. JCS: was in charge of gathering all the scientific material concerning our paper. He reviewed all the references and compared the information of all sources. He was also in charge of getting the patient’s consent form.
Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.
Competing interests None declared.
Patient consent Obtained.
Provenance and peer review Not commissioned; externally peer reviewed.