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CASE REPORT
Giant coronary artery aneurysms in a 12-week-old infant with incomplete Kawasaki disease
  1. Lucy Guile1,2,
  2. Simon Parke3,
  3. Alison Kelly4,
  4. Robert Tulloh1,5
  1. 1 School of Clinical Sciences, University of Bristol, Bristol, UK
  2. 2 Department of Paediatric Surgery, Bristol Royal Hospital For Children, Bristol, UK
  3. 3 Department of Paediatrics, Royal Devon and Exeter NHS Foundation Trust, Exeter, UK
  4. 4 Department of Paediatric Rheumatology, Bristol Royal Hospital for Children, Bristol, UK
  5. 5 Department of Paediatric Cardiology, Bristol Royal Hospital For Children, Bristol, UK
  1. Correspondence to Dr Lucy Guile, lucyguile{at}doctors.org.uk

Summary

Kawasaki disease (KD) is an acute inflammatory vasculitis that occurs worldwide and disproportionately affects male children, most commonly between the ages of 6 months and 5 years. KD can present with only a few features and thus be difficult to diagnose, particularly in the youngest and oldest patients. We describe a 12-week-old Caucasian female infant who presented with rash and fever but no other features of KD, who developed giant coronary artery aneurysms. Considering how common is the presentation of a febrile infant with a rash, this case highlights the importance of considering KD early in the differential diagnosis for any infant with unexplained fever. Furthermore, it emphasises how echocardiography can help in the investigation of a febrile child with no clear source of infection.

  • paediatrics
  • vasculitis
  • cardiovascular medicine

This is an Open Access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/

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Footnotes

  • Contributors LG wrote the initial draft. AK, SP and RT amended the draft and approved the final version. RT obtained the echocardiography images.

  • Funding The authors have not declared any specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Patient consent Parental/guardian consent obtained.

  • Provenance and peer review Not commissioned; externally peer reviewed.