BMJ Case Reports 2018; doi:10.1136/bcr-2018-224365
  • Rare disease

Acute acalculous cholecystitis of an intrahepatic gallbladder causing Mirizzi’s syndrome

  1. Gurpal Sandha1
  1. 1Department of Gastroenterology, University of Alberta, Edmonton, Alberta, Canada
  2. 2Department of Radiology and Diagnostic Imaging, University of Alberta, Edmonton, Alberta, Canada
  3. 3Department of General Surgery, University of Alberta, Edmonton, Alberta, Canada
  1. Correspondence to Dr Vanessa Falk, vfalk{at}
  • Accepted 7 April 2018
  • Published 13 April 2018


We present the case of a young female with symptoms of biliary colic and a biochemical profile consistent with biliary obstruction. Imaging was suspicious for Mirizzi’s syndrome. Intraoperatively, the patient was found to have a complete intrahepatic gallbladder causing common hepatic duct compression with final pathology confirming acute cholecystitis. We review the embryological development of the gallbladder as well as clinical presentation of Mirizzi’s syndrome. Special consideration for clinical workup and surgical management is discussed.


  • Contributors VF wrote the manuscript. GL, DB and GS reviewed the manuscript. GL provided the images. GS edited the manuscript and is the article guarantor. All authors approved the final version of this manuscript.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Patient consent Obtained.

  • Provenance and peer review Not commissioned; externally peer reviewed.

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