Article Text
Summary
Common variable immunodeficiency (CVID) refers to a group of disorders where differentiation and maturation of B cells into plasma cells are affected, leading to decreased or defective immunoglobulin production and subsequent immunodeficiency. Symptoms may present at any age between 5 and 72 years, although more severe forms often manifest earlier in life. Milder forms may not be detected. We present an intriguing case of a 69-year-old man presenting with recurrent pneumonia caused by a rare organism Staphylococcus lugdunensis, eventually determined to be caused by CVID. The patient had a good clinical outcome after receiving immunoglobulin replacement therapy.
- respiratory system
- pneumonia (infectious disease)
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Footnotes
Contributors NCM organised the literature review for this study, wrote the initial draft of this paper, was part of the team that treated the patient, identified this case as unusual and worthy of a case report, and finalised the discussion. SVAV participated in the literature review, helped with formatting of images and paper, and helped with the initial draft of the discussion. JT did an extensive editing of this paper, and rewrote most of the background, case presentation and discussion, and made sure there were no plagiarised sentences. He was part of the team that cared for the patient.
Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.
Competing interests None declared.
Patient consent Obtained.
Provenance and peer review Not commissioned; externally peer reviewed.