Article Text
Summary
This is a case of a 20-year-old woman who presented with a left jaw mass which was resected and found to be a giant cell granuloma of the mandible. Her history and physical examination were suggestive for Noonan syndrome which was confirmed with genetic testing and the finding of a PTPN11 gene mutation which has rarely been associated with giant cell lesions of the jaw. Given her particular genetic mutation and the presence of a giant cell lesion, we present a case of Noonan-like/multiple giant cell lesion syndrome.
- endocrine system
- calcium and bone
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Footnotes
Contributors BPS initially saw and evaluated the patient and confirmed her suspicion of a diagnosis of Noonan syndrome with genetic testing. MP drafted the case report with discussion and BPS critically revised the content and finally approved the case report for submission. Both authors are accountable for the content of the case report and are willing to address any questions regarding its content.
Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.
Competing interests None declared.
Patient consent Obtained.
Provenance and peer review Not commissioned; externally peer reviewed.