Article Text

Download PDFPDF
CASE REPORT
Leiomyosarcoma: a rare sinonasal malignancy
  1. Matthew Ming Kei Kwok1,
  2. Stewart Lee1,
  3. Patrick Hosking2
  1. 1Department of ENT, Eastern Health, Box Hill, Victoria, Australia
  2. 2Department of Pathology, Eastern Health, Box Hill, Victoria, Australia
  1. Correspondence to Dr Matthew Ming Kei Kwok, mattmkkwok{at}gmail.com

Summary

Leiomyosarcomas (LMS) are rare sinonasal malignant tumours with 20 cases of nasal LMS previously reported in the literature. An 81-year-old man presented with an incidental left nasal lesion associated with left nasal obstruction and occasional left-sided blood-stained rhinorrhoea. Nasendoscopic examination showed green coloured polyps filling the left nasal cavity with biopsies showing LMS. CT imaging did not show any bony erosion. No metastases were found on positron emission tomography imaging. The patient underwent endoscopic resection and all surgical margins were clear of disease. The patient was declined postoperative radiotherapy, and serial follow-up has not shown any recurrence to date. Nasal LMS are rare sinonasal smooth muscle tumours and symptoms and radiological findings are often non-specific. Therefore, diagnosis is made on histopathological and immunohistochemical analysis. Due to their invasive nature, the treatment of choice is complete surgical resection, with adjuvant therapy reserved for patients with locally advanced or metastatic disease.

  • otolaryngology / ent
  • head and neck cancer

Statistics from Altmetric.com

Request Permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.

Footnotes

  • Contributors This original manuscript has been approved by all authors and has not been previously submitted to any other journal. Data collection and CT images were obtained by MMKK. Pathological images were provided by PH. MMKK and SL were involved with the preparation of the manuscript.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Patient consent Obtained.

  • Provenance and peer review Not commissioned; externally peer reviewed.