BMJ Case Reports 2018; doi:10.1136/bcr-2017-223881
  • Reminder of important clinical lesson

Osteoporosis and malignancy: a dicey combination

  1. Sadishkumar Kamalanathan
  1. Department of Endocrinology, Jawaharlal Institute of Postgraduate Medical Education and Research, Pondicherry, India
  1. Correspondence to Dr Sadishkumar Kamalanathan, sadishkk{at}
  • Accepted 18 May 2018
  • Published 11 June 2018


Osteoporosis is the most common metabolic bone disorder worldwide, especially in women. Postmenopausal status is the most common risk factor for osteoporosis in elderly women. The operational diagnosis of osteoporosis is usually made with the help of central dual energy X-ray absorptiometry scan. Clinically, osteoporosis is suspected in the background of one or more fractures of the hip, vertebra, proximal humerus or pelvis in the absence of local disease or high-energy trauma. Serious underlying illness can present with vertebral fractures and can be missed if other clues from clinical examination and investigations are overlooked. We report a case emphasising this aspect.


  • Contributors NLP and JS managed the patient, prepared the manuscript. JPS and SK supervised the management of the patient, reviewed and edited the manuscript.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Patient consent Next of kin consent obtained.

  • Provenance and peer review Not commissioned; externally peer reviewed.

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