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Uncommon cause of hypercalcaemia in metastatic breast carcinoma
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  1. Rohit Barnabas1,
  2. Ashish Singh2,
  3. Mazhuvanchary Jacob Paul3,
  4. Thomas Vizhalil Paul4
  1. 1Department of Endocrinology, Diabetes and Metabolism, Christian Medical College, Vellore, India
  2. 2Department of Medical Oncology, Christian Medical College, Vellore, India
  3. 3Department of Endocrine Surgery, Christian Medical College, Vellore, India
  4. 4Christian Medical College, Vellore, India
  1. Correspondence to Professor Thomas Vizhalil Paul, thomasvpaul{at}yahoo.com

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Description

A 61-year-old female diagnosed to have carcinoma of the left side with disseminated skeletal metastases (figure 1) 5 years back presented with worsening bone pains and fatigability for the past 6 months. She was earlier treated with palliative radiotherapy to the spine and had been on oral letrozole; this was followed by a palliative mastectomy. In addition, she received parenteral bisphosphonates for metastases. Clinical examination was unremarkable. Blood biochemistry showed elevated calcium 12.8 mg/dL (N: 8.3–10.4) with an alkaline phosphatase of 61 U/L (N: 40–125) and creatinine of 0.7 mg/dL (N: 0.6–1.2), 25 OH vitamin D of 26 ng/mL (N: 30–75 ng/mL) and elevated …

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Footnotes

  • Contributors RB wrote the manuscript. AS, MJP and TVP reviewed, revised and approved the manuscript.

  • Funding This research received no specific grant from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Patient consent Obtained.

  • Provenance and peer review Not commissioned; externally peer reviewed.