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CASE REPORT
Hyperkalaemic periodic paralysis in pregnancy
  1. Soon-Leong Yong1,
  2. Teik-Hoy Sin1,
  3. Eric Boon-Kiat Tang2,3,
  4. Ming-Cheng Chai4
  1. 1Department of Obstetrics and Gynaecology, Sibu Hospital, Sibu, Sarawak, Malaysia
  2. 2Faculty of Medicine, SEGi University Sibu Clinical Campus, Sibu, Sarawak, Malaysia
  3. 3Department of Anaesthesiology, Sibu Hospital, Sibu, Sarawak, Malaysia
  4. 4Department of Obstetrics and Gynaecology, Sarikei Hospital, Sarikei, Sarawak, Malaysia
  1. Correspondence to Dr Eric Boon-Kiat Tang, aerikh{at}gmail.com

Summary

Hyperkalaemic periodic paralysis is a rare skeletal muscle disorder which is characterised by episodic muscle paralysis associated with hyperkalaemia. Although it is an autosomal-dominant disease, cases of de novo mutations have been reported. We report the case of a 30-year-old woman, gravida 5 para 3+1, who was planned for an elective repeated caesarean section at 38 weeks and 3 days of pregnancy. She developed recurrent episodes of hyperkalaemic periodic paralysis after receiving corticosteroids. Intravenous calcium gluconate was administered to normalise potassium levels (from 6.3 mmol/L to 4.1 mmol/L). Extra anaesthetic precautions were taken during the caesarean delivery. Postoperatively, she was well and discharged from the ward. She encountered similar symptoms in her third pregnancy, and there was no family history of muscle weakness which suggested a de novo mutation. Pregnancy seemed to result in vulnerability to hyperkalaemic attacks as she was never symptomatic outside pregnancy.

  • anaesthesia
  • medical management
  • pregnancy

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Footnotes

  • Contributors S-LY, T-HS, EB-KT and M-CC contributed to conception, design, writing of abstract and case report.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Patient consent Obtained.

  • Provenance and peer review Not commissioned; externally peer reviewed.