BMJ Case Reports 2018; doi:10.1136/bcr-2017-223243
  • Unusual presentation of more common disease/injury

Isolated splenic mucormycosis in a case of aplastic anaemia

  1. Manphool Singhal4
  1. 1Department of Internal Medicine, Post Graduate Institute of Medical Education and Research (PGIMER), Chandigarh, Candigarh, India
  2. 2Department of Internal Medicine, Post graduate Institute of Medical Education and Research, Chandigarh, Chandigarh, India
  3. 3Department of Histopathology, Postgraduate Institute of Medical Education and Research, Chandigarh, India
  4. 4Department of Radiodiagnosis, Postgraduate Institute of Medical Education and Research, Chandigarh, Chandigarh, India
  1. Correspondence to Dr Shefali K Sharma, sharmashefali{at}
  • Accepted 26 January 2018
  • Published 8 February 2018


Mucormycosis, a rare opportunistic infection seen in immunocompromised hosts, is caused by fungi of Mucorales family. It may be confined to the organs, such as rhinocerebral and pulmonary mucormycosis, or may cause disseminated infection. A 14-year-old boy presented to our clinic with fever and left upper quadrant abdominal pain, and on evaluation was found to have pancytopaenia, and imaging revealed ill-defined splenic collection with thrombus in the splenic vein. He was started on empirical intravenous antibiotics, followed by antifungals empirically as he did not show any improvement clinically. Eventually, splenectomy was done, which on histopathological examination revealed mucormycosis. The patient finally succumbed to his illness as he developed peritonitis and refractory shock. To date, only two cases of isolated splenic mucormycosis have been reported. Aggressive treatment is needed, which includes the use of antifungals (amphotericin B) and surgical debridement or resection of the involved tissues or organs.


  • Contributors SKS treated the case and came up with the idea of writing the case report. PB prepared the manuscript. BR did the histopathological examination. MS reported the radiology.

  • Competing interests None declared.

  • Patient consent Parental/guardian consent obtained.

  • Provenance and peer review Not commissioned; externally peer reviewed.

Register for free content

The full text of all Editor's Choice articles and summaries of every article are free without registration

The full text of Images in ... articles are free to registered users

Only fellows can access the full text of case reports (apart from Editor's Choice) - become a fellow today, or encourage your institution to, so that together we can grow and develop this resource

Don't forget to sign up for content alerts so you keep up to date with all the case reports as they are published, and let us know what you think by commenting on the Editor's blog

Navigate This Article