BMJ Case Reports 2018; doi:10.1136/bcr-2017-223229
  • Reminder of important clinical lesson

Rhabdomyolysis: a rare complication of Hashimoto’s thyroiditis precipitated by statin therapy

  1. Ummer Karadan3
  1. 1Department of Nephrology, Baby Memorial Hospital, Calicut, Kerala, India
  2. 2Department of Internal Medicine, Baby Memorial Hospital, Calicut, Kerala, India
  3. 3Department of Neurology, Baby Memorial Hospital, Calicut, Kerala, India
  1. Correspondence to Dr Robin George Manappallil, drrobingeorgempl{at}
  • Accepted 9 January 2018
  • Published 12 February 2018


Hashimoto’s thyroiditis (HT) or chronic lymphocytic thyroiditis is the most common form of primary hypothyroidism. Muscular manifestations like weakness, pain, stiffness and elevated muscle enzymes have been noticed in hypothyroidism. Statins are also known to cause myositis and rhabdomyolysis. This is a case of a middle-aged man, on statin therapy, who presented with severe muscle aches and pain and was found to have rhabdomyolysis. Further evaluation revealed an underlying HT as the culprit for his condition. He was managed with intravenous fluids and levothyroxine along with cessation of statins, following which he improved.


  • Contributors JP: critical revision of manuscript and treating nephrologist. RGM: concept and design of case report, reviewed the literature, manuscript preparation and treating physician. UK: critical revision of manuscript and treating neurologist.

  • Funding This research received no specific grant from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Patient consent Obtained.

  • Provenance and peer review Not commissioned; externally peer reviewed.

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