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Rare disease
CASE REPORT
Coexisting squamous cell carcinoma and high-grade neuroendocrine carcinoma, small cell type: a rare collision in cervix
  1. Seema Kaushal1,
  2. Sandeep R Mathur1,
  3. Sunesh Kumar2
  1. 1Department of Pathology, All India Institute of Medical Sciences, New Delhi, India
  2. 2Department of Obstetrics and Gynaecology, All India Institute of Medical Sciences, New Delhi, India
  1. Correspondence to Dr Seema Kaushal, seema.dr{at}gmail.com

Summary

Collision tumours of the uterine cervix are extremely uncommon with exact incidence not known. Unlike squamous cell carcinoma (SCC) and adenocarcinoma that are known to coexist, small cell neuroendocrine carcinoma (SCNEC) is rarely documented with other histological types in the cervix. We report such rare case of a collision tumour in cervix displaying dual histological component of SCNEC and SCC in a 36-year-old woman. The case is being presented because of its rarity and represents a unique and hitherto seldom-reported combination of two malignant tumours with distinct and often contrasting epidemiology, histology and prognosis coexisting in the same patient.

  • pathology
  • urinary and genital tract disorders

https://doi.org/10.1136/bcr-2017-223127

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    Footnotes

    • Contributors SKa: acquisition and interpretation of data, conception, design and drafting of the manuscript. SRM and SKu: acquisition and interpretation of data, critical review of the manuscript.

    • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

    • Competing interests None declared.

    • Patient consent Obtained.

    • Provenance and peer review Not commissioned; externally peer reviewed.