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Unusual presentation of more common disease/injury
CASE REPORT
Cutaneous herald: leukaemia cutis as presenting manifestation of relapse in acute promyelocytic leukaemia
  1. Prasanth Balasubramanian,
  2. Ram V Nampoothiri,
  3. Deepak Goni,
  4. Pankaj Malhotra
  1. Department of Internal Medicine, Post Graduate Institute of Medical Education and Research, Chandigarh, India
  1. Correspondence to Dr Pankaj Malhotra, hematpgi{at}gmail.com

Summary

Leukaemia cutis or cutaneous infiltration of neoplastic myeloid or lymphoid cells is usually seen in the acute myelomonocytic and acute monocytic variants of acute myeloid leukaemia. Here, we report a case of acute promyelocytic leukaemia who achieved remission, presenting with skin lesions, the biopsy of which revealed leukaemia cutis, heralding the relapse of the disease. After establishing the diagnosis with bone marrow analysis, the patient was started on daunorubicin chemotherapy along with arsenic trioxide and all-trans retinoic acid. Afterwards, the skin lesions resolved, and the patient is planned for consolidation with bone marrow transplantation.

  • haematology (incl blood transfusion)
  • dermatology

https://doi.org/10.1136/bcr-2017-222906

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    Footnotes

    • Contributors PB: preparation of manuscript. RVN: literature review and preparation of manuscript. DG: managing the index case. PM: concept, design and managing the index case.

    • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

    • Competing interests None declared.

    • Patient consent Obtained.

    • Provenance and peer review Not commissioned; externally peer reviewed.