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CASE REPORT
Breast cancer metastasis to the bladder: a literature review
  1. Adam M Kase1,
  2. David Menke2,
  3. Winston Tan3,4
  1. 1Department of Internal Medicine, Mayo Clinic’s Campus in Florida, Jacksonville, Florida, USA
  2. 2Department of Pathology, Mayo Clinic’s Campus in Florida, Jacksonville, Florida, USA
  3. 3Department of Hematology, Mayo Clinic’s Campus in Florida, Jacksonville, Florida, USA
  4. 4Department of Oncology, Mayo Clinic’s Campus in Florida, Jacksonville, Florida, USA
  1. Correspondence to Dr Adam M Kase, kase.adam{at}mayo.edu

Summary

Given the prevalence of breast cancer and the mortality associated with metastatic disease, it is imperative for physicians to not only be aware of common sites but also of rare metastatic destinations such as the bladder. A postmenopausal woman with a medical history of stage 2 invasive ductal carcinoma, oestrogen receptor/progesterone receptor positive and human epidermal growth factor receptor 2 negative, in remission for 9 years, presented to her primary care physician with concerns of increased urinary urgency, frequency and incontinence. The patient underwent cystoscopy with biopsy of an area of granulation tissue. Biopsy revealed adenocarcinoma consistent with breast primary. The common sites of metastases from breast cancer are lung, bone and liver. This case is unique where breast cancer was found to metastasise to the bladder. It is important for physicians to consider further investigation when a breast cancer survivor develops urinary symptoms even without haematuria.

  • breast cancer
  • urological cancer
  • urology

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Footnotes

  • Contributors AK was the primary author and lead investigator in acquiring data and performing the literature review. DM provided manuscript revisions/intellectual guidance with his area of expertise and approval of the final version of the manuscript to be published. WT was responsible for the development of literature design and interpretation/analysis of the literature. He offered assistance with revisions and approval of the final manuscript version for publication.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Patient consent Not required.

  • Provenance and peer review Not commissioned; externally peer reviewed.