BMJ Case Reports 2017; doi:10.1136/bcr-2017-222093
  • Images in…

Tamoxifen maculopathy in a male patient

  1. Rohan Chawla
  1. Department of Ophthalmology, Dr. Rajendra Prasad Centre for Ophthalmic Sciences, AIIMS, New Delhi, India
  1. Correspondence to Dr Amar Pujari, dramarpujari{at}
  • Accepted 27 August 2017
  • Published 7 September 2017


Case description

A 28-year-old male patient presented with the history of blurring of vision in both the eyes for the past 5 months. The patient was a diagnosed case of desmoid fibromatosis of the right axilla 8 years back. The tumour was initially debulked followed by four cycles of systemic chemotherapy, after which patient was symptom-free for 3 years. The patient noticed an increment in the tumour size, for which he consulted another oncologist. A repeat biopsy was done, which proved the same findings. The patient was started on a combination of tamoxifen 80 mg/day and celecoxib 200 mg/day. He had received tamoxifen at a cumulative dose of 116 g over 4 years. Examination in our clinic revealed visual acuity of 20/20 in both eyes with unremarkable anterior chamber findings. Intraocular pressure was 14 and 16 mm Hg in right and left eye, respectively. Fundus showed bilateral crystalline refractile deposits in …

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