Article Text
Summary
A small proportion of gastrointestinal angiodysplasia bleeding leads to chronic blood cell transfusion dependency. There are no guidelines supporting decision-making among various treatments in patients with gastrointestinal angiodysplasia bleeding. When endoscopic argon plasma coagulation is ineffective, the angiogenesis inhibitors thalidomide and octreotide can be considered. We describe a 77-year-old woman who had side effects of these angiogenesis inhibitors, which caused her to have continued bleeding. She was successfully treated with tranexamic acid with a substantial decrease in need for red blood cell transfusions.
- Gi Bleeding
- Drugs: Gastrointestinal System
- Small Intestine
- Haematology (incl Blood Transfusion)
- Pharmacology And Therapeutics
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Footnotes
Contributors KVG: acquisition of data, analysis and/or interpretation of data, and drafting the manuscript. EJMvG: revising the manuscript critically for important intellectual content. JPHD: revising the manuscript critically for important intellectual content.
Competing interests None declared.
Patient consent Obtained.
Provenance and peer review Not commissioned; externally peer reviewed.