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Novel treatment (new drug/intervention; established drug/procedure in new situation)
CASE REPORT
Metastatic melanoma: a rare cause of central airway obstruction
  1. Mohamed Faisal Abdul Hamid1,
  2. Andrea Ban Yu-Lin1,
  3. Tidi Maharani Hassan1,
  4. Nurashikin Mohammad2
  1. 1Medical Department, Pusat Perubatan Universiti Kebangsaan Malaysia, Cheras, Malaysia
  2. 2Department of Internal Medicine, Universiti Sains Malaysia, Kota Bharu, Malaysia
  1. Correspondence to Dr Nurashikin Mohammad, elshikina{at}gmail.com

Summary

A middle-aged woman with recurrent malignant melanoma presented initially with massive left pleural effusion. There was a complete obliteration of the left main bronchus on flexible bronchoscopy caused by a mass. Serial cryo-debulking of the tumour was done under rigid bronchoscopy; however, the outcome was not favourable due to the aggressive tumour growth. Vemurafenib was planned after thoracic radiation. She was not keen for the biologics treatment due to financial constraints. We report a case of central airway obstruction due to recurrent aggressive melanoma. More evaluations are needed on the role of interventional pulmonologist for bronchoscopic debulking of this rapidly growing tumour as well as the role of biological agents in treating such cases.

  • respiratory system
  • respiratory cancer
  • dermatology
  • malignant disease and immunosuppression

https://doi.org/10.1136/bcr-2017-221545

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    Footnotes

    • Contributors MFAH and NM contributed to the conception and design of case report and were responsible for the acquisition of data. ABY-L interpreted and analysed the data. TMH drafted the article and revising it critically especially for the intellectual content. All authors had approved the final version for publications and also accountable for the accuracy of data and overall integrity.

    • Competing interests None declared.

    • Patient consent Obtained.

    • Provenance and peer review Not commissioned; externally peer reviewed.