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Summary
Although thrombocytopenia is known to be associated with pathogenesis of retinopathy of prematurity (ROP), immune thrombocytopenic purpura (ITP) is rare in infancy and not reported to occur with ROP. A preterm infant with aggressive posterior ROP developed bilateral massive subconjunctival haemorrhage after scleral indentation during screening. On evaluation, the infant was found to have severe ITP. Following intravenous transfusion of platelets and immunoglobulin, platelet counts improved and subconjunctival haemorrhage resolved over time. This case highlights the unusual presentation of ITP and also discusses the association of thrombocytopenia with ROP. Ophthalmologists should get prompt haematological work-up of such occurrences.
- retina
- infant health
- haematology (including blood transfusion)
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Footnotes
Contributors PC: substantial contributions to the conception/design of work; drafting the work; final approval of the version. DK: substantial contributions to the conception/design of work; acquisition, analysis, interpretation of data; drafting the work; final approval of the version. VK and RT: interpretation of data for the work; revising it critically for important intellectual content; final approval of the version. All authors agreed to be accountable for all aspects of work.
Competing interests None declared.
Patient consent Guardian consent obtained.
Provenance and peer review Not commissioned; externally peer reviewed.