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Unusual association of diseases/symptoms
CASE REPORT
An unusual cause of isolated secondary ovarian failure due to cerebral toxoplasmosis in an African woman with AIDS
  1. Katie Tharshana Yoganathan1,
  2. Shaheena Sadiq2,
  3. Kathir G Yoganathan3
  1. 1 West Middlesex University Hospital NHS Trust, Isleworth, UK
  2. 2 Department of Neuroradiology, Morriston Hospital, Swansea, UK
  3. 3 ABM University Health Board, Singleton Hospital, GUM/HIV, Swansea, UK
  1. Correspondence to Dr Kathir G Yoganathan, kathir.yoganathan{at}wales.nhs.uk

Summary

Primary ovarian failure is common. However, isolated secondary ovarian failure due to gonadotrophin deficiency is rare. A few cases of isolated gonadotrophin deficiency, due to congenital cerebral toxoplasmosis, have been described in children. We report the case of a 34-year-old African woman positive for HIV, who developed secondary amenorrhoea following the successful treatment of cerebral toxoplasmosis. Investigations revealed that she developed an isolated gonadotrophin deficiency due to pituitary lesion. The rest of the pituitary function dynamic tests were normal.

  • infections
  • pituitary disorders
  • H\iv / Aids
  • infection (neurology)

https://doi.org/10.1136/bcr-2017-221337

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    Footnotes

    • Contributors KTY undertook student-selected module on neurological complications of HIV when she was a final year medical student, selected five cases of neurological complications of HIV (this case was one of them) and wrote a case report. SS reported MRI scan and provided this patient's images. KGY, Consultant, was in charge of clinical management of this patient.

    • Competing interests None declared.

    • Patient consent Obtained.

    • Provenance and peer review Not commissioned; externally peer reviewed.