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Rare disease
CASE REPORT
Eosinophilic myocarditis as a first presentation of eosinophilic granulomatosis with polyangiitis (Churg-Strauss syndrome)
  1. Ronan Bluett1,
  2. David McDonnell1,
  3. Claire O’Dowling1,2,
  4. Carl Vaughan1,2
  1. 1Department of Cardiology, Mercy University Hospital, Cork, Ireland
  2. 2Department of Cardiology, Cork University Hospital, Cork, Ireland
  1. Correspondence to Dr Ronan Bluett, ronanbluett{at}gmail.com

Summary

We present the case of a 28-year-old man who presented with chest pain and elevated cardiac biomarkers, with no evidence of acute ischaemia. He had a pronounced eosinophilia, abnormal echocardiographic, cardiac MRI and CT findings. He underwent transbronchial biopsy of carinal lymph nodes and of lung parenchyma. Endomyocardial biopsy yielded an eosinophilic infiltrate. He was treated with high dose glucocorticoids and made a rapid recovery. Testing for FIP1L1-PDGFRA and other BCR-ABL1 mutations was negative. Ultimately, he was diagnosed with eosinophilic granulomatosis with polyangiitis, also known as Churg-Strauss syndrome.

  • cardiovascular medicine
  • interventional cardiology
  • clinical diagnostic tests
  • radiology (diagnostics)
  • vasculitis

This is an Open Access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/

https://doi.org/10.1136/bcr-2017-221227

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    Footnotes

    • Contributors RB is the main author. DM performed literature review and helped to collate all laboratory results and so on for this paper. COD provided guidance and advice on how to construct the discussion and edited multiple drafts of the paper. CV edited multiple drafts of the paper and provided guidance and teaching to all the authors.

    • Competing interests None declared.

    • Patient consent Obtained.

    • Provenance and peer review Not commissioned; externally peer reviewed.