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A 69-year-old man with a history of hypercholesterolaemia presented to the emergency department with atypical chest pain. Physical examination was normal and ECG showed no evidence of ischaemic changes. Laboratory studies were notable for a D-dimer level of 1842 ng/mL (reference value <500 ng/mL) and the troponin I level was normal.
Chest X-ray was normal. Chest CT angiography ruled out a pulmonary embolism but showed a giant and extensive aneurysm of the right coronary artery (RCA) up to 45 mm in diameter with a partly thrombosed lumen and evidence of right ventricle compression on four-chamber view (figures 1 and 2). The volume of the aorta and the RCA appeared similar (figure 3). Doppler echocardiography did not demonstrate right or left heart haemodynamic abnormalities.
Diagnostic coronary angiography showed atheroma and ectasia on the left descending coronary artery and the circumflex. Linked to the very large lumen, the cannulation of the RCA was difficult and the coronary flow appeared slow and very turbulent (figure 4).
Symptoms at presentation resolved and cardiac MRI showed no evidence of myocardial infarction. There were no other aneurysm locations, especially in cerebral arteries or descending aorta.
Complications of coronary aneurysm include compression, rupture, embolisation or thrombosis, and treatment is not consensual.1 2 Due to these risks, an interventional approach with surgery or percutaneous coronary intervention was considered but was refused by the patient.
Because of persistent elevation of D-dimer at 1 month (1590 ng/mL), an evidence of coagulation activation process probably related to the aneurysm, oral anticoagulation, rather than antiplatelet therapy, could represent the antithrombotic therapy of choice in such cases and was prescribed to the patient. Ten months after the diagnosis and initiation of medical therapy, the patient was asymptomatic and did not experience complication.
Learning points
There are no data reported in the literature regarding treatment and indication of surgical or percutaneous management for such aneurysms.
Medical treatment could be considered in such case.
No comparison between medical therapy and interventional approach has been made.
There are no data regarding the best medical therapy (antiplatelet vs anticoagulation therapy).
Footnotes
Contributors VS, JGD, RD and PH contributed to the planning, conduct and report of the work describe in this article. VS and PH are responsible for the overall content.
Competing interests None declared.
Patient consent Obtained.
Provenance and peer review Not commissioned; externally peer reviewed.