Article Text
Summary
A 63-year-old man presented with a pulsatile cutaneous horn on the nose and multiple angiomatous nodules on the gingiva and scalp, which appeared over 2 months. He had severe hypercalcaemia, lytic lesions in multiple bones and acute kidney injury. Excision biopsy from the gingival nodule showed a clear cell neoplasm. The bone marrow showed atypical cells with similar morphology. Imaging showed a 7 cmx7.5 cm mass at the upper pole of the left kidney with metastases to the bones, liver and lung. Immunohistochemistry was consistent with metastatic renal cell carcinoma. Renal cell carcinoma presenting as a cutaneous horn is extremely rare and to the best of our knowledge only one other case was found in the literature. There was visible regression in the size of the cutaneous horn and nodules following initiation of pazopanib therapy. However, he succumbed to his illness a month later.
- Urological Cancer
- Pathology
- Acute Renal Failure
- Calcium And Bone
- Dermatology
Statistics from Altmetric.com
Footnotes
Contributors JTG and AJM were involved in the primary evaluation of the patient, conception and drafting of the case report, reviewing existing literature and revising the report. AAG was involved in characterizing the lesion, biopsy of the lesion, reviewing existing literature and revising the report. JC was involved in providing the final histopathological diagnosis and revising the report. JTG is a guarantor.
Competing interests None declared.
Patient consent Obtained.
Provenance and peer review Not commissioned; externally peer reviewed.