Article Text
Summary
A middle-aged man with decompensated cirrhosis and a dimorphic multisite skin rash is diagnosed with rare atypical herpes simplex infection, manifesting Sweet’s syndrome (SS) in the absence of other described associations. SS, an acute febrile neutrophilic dermatosis, has three common forms—classical or idiopathic, malignancy associated and drug induced. Systemic autoimmune, connective tissue diseases and infections are also strong associations. The latter is commonly described in Gram-positive bacteria, salmonellosis and Yersinia. Herpes infections are a rare cause of SS, reported only thrice in literature, one with concomitant lupus, the second with associated mycobacterial infection and third, in metastatic breast disease in contrast to our patient. Atypical rash, especially if dimorphic, warrants histopathological evaluation to confirm underlying disease.
- gastroenterology
- cirrhosis
- infectious diseases
- intensive care
- pathology
Statistics from Altmetric.com
Footnotes
Contributors CAP contributed to the conception and design, data acquisition, drafting and revising the article, and final approval of the published version. RP contributed to the conception and design, data acquisition, critically revising the article and final approval of the published version. PA contributed to the data acquisition and final approval of the published version.
Competing interests None declared.
Patient consent Obtained.
Provenance and peer review Not commissioned; externally peer reviewed.