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CASE REPORT
Myocardial infarction masquerading as myocarditis in a patient with factor V Leiden: unmasked with MR
  1. Jason Leo Walsh1,
  2. Benjamin Howell Lole Harris2,
  3. Walid Gharzuddine1,
  4. Hussain Isma'eel1
  1. 1 American University of Beirut Medical Center, Beirut, Lebanon
  2. 2 Department of Oncology, University of Oxford, Oxford, UK
  1. Correspondence to Hussain Isma'eel, hi09{at}aub.edu.lb

Summary

We present a case of a 21-year-old man presenting with sharp left-sided chest pain. A CT pulmonary angiogram was negative, ECG was unremarkable and a mild troponin rise was observed. Myocarditis was suspected as the most likely diagnosis, particularly in view of the patient’s previous diagnosis of myocarditis 3 years prior. A cardiac MRI was indicative of an acute mid-anterior myocardial infarction (MI) and an old inferior MI with an associated aneurysm. A subsequent angiogram revealed a subtotal occlusion in the second diagonal artery, likely precipitated by homozygous factor V Leiden.

This case illustrates the value of MRI in differentiating acute MI from myocarditis when clinical suspicion is low, as in this young patient with atypical chest pain. Further, it demonstrates the value of MRI in detecting previous MIs and reinforces the importance of searching for precipitants of MI in young patients.

  • Cardiovascular Medicine
  • Radiology
  • Ischaemic Heart Disease

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Footnotes

  • Contributors All authors contributed to the conception, design andacquisition of data. JLW and BH drafted the first version of the article. Aftercomments, JLW and BH helped revise the article. WG and HI’ commented on thefirst draft of the article and help revise it. All authors approve thesubmitted version to be published and are happy to be accountable for thearticle.

  • Competing interests None declared.

  • Patient consent Obtained.

  • Provenance and peer review Not commissioned; externally peer reviewed.