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Unusual presentation of more common disease/injury
CASE REPORT
A reminder of Escherichia coli sepsis-induced reversible cardiomyopathy
  1. Aung Naing Lin1,
  2. Atif Shaikh2,3,
  3. Sithu Lin1,
  4. Deepika Misra3
  1. 1 Department of Internal Medicine, The Brooklyn Hospital Center, Brooklyn, New York, USA
  2. 2 Department of Cardiology, The Brooklyn Hospital Center, Brooklyn, New York, USA
  3. 3 Department of Cardiology, Mount Sinai Beth Israel, New York City, New York, USA
  1. Correspondence to Dr Sithu Lin, dr.sithulin{at}gmail.com

Summary

Cardiomyopathy is a progressive disease of myocardium causing either mechanical or electrical disturbances. Sepsis-induced cardiomyopathy (SICM) is an entity of cardiomyopathy which is reversible in 1–2 weeks after recovery from sepsis or septic shock. SICM is thought to have unpredictable cumulative mortality towards sepsis but its exact mechanism remains elusive. We report a case of Escherichia coli SICM in a 63-year-old woman presented with sudden onset of dyspnoea on exertion and orthopnoea following nausea, vomiting and diarrhoea after consuming Chinese foods. Transthoracic echocardiogram revealed severely reduced global left ventricular ejection fraction (LVEF) of <20% which returned back to normal LVEF of 57% after 10 days. Subsequent cardiac catheterisation showed non-obstructive coronaries. No specific therapy intended for reversal of SICM presents to date despite current sepsis survival guideline available for haemodynamic support. Initiation of beta blockers after recovery from septic shock has been beneficial.

  • Cardiovascular system
  • Infections
  • Respiratory system

https://doi.org/10.1136/bcr-2017-220556

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    Footnotes

    • Contributors ANL was involved in conception of the idea, manuscript preparation, assay analysis and interpretation. AS was involved in patient care, conception of the idea and manuscript preparation. SL was involved in manuscript preparation, correlative assays and interpretation. DM was involved in conception of the idea, assay analysis and proofreading. All the authors approved the submitted manuscript.

    • Competing interests None declared.

    • Patient consent Obtained.

    • Provenance and peer review Not commissioned; externally peer reviewed.