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CASE REPORT
Aspirin safety in glucose-6-phosphate dehydrogenase deficiency patients with acute coronary syndrome undergoing percutaneous coronary intervention
  1. Julien Feghaly1,2,
  2. Abdul Rahman Al Hout1,2,
  3. Mattew Mercieca Balbi2
  1. 1St George’s, University of London, London, UK
  2. 2Department of Cardiology, Mater Dei Hospital, Msida, Malta
  1. Correspondence to Dr Julien Feghaly, feghaly.julien{at}gmail.com

Summary

The use of aspirin, as part of a dual antiplatelet therapy regimen, is an established standard following coronary stenting in patients suffering from acute coronary syndrome (ACS). However, in glucose-6-phosphate dehydrogenase (G6PD) deficient patients, precaution is always taken with aspirin use, due to the risk of haemolysis. We reviewed all previous cases of G6PD deficient patients with ACS, in addition to a review of the available literature, to better understand the safety of aspirin use in this population. To date, there are no reported cases of haemolysis following aspirin use in this patient group and no guideline is established to date.

  • cardiovascular medicine
  • interventional cardiology
  • ischaemic heart disease

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Footnotes

  • Contributors JF is the first and major author of the submission. ARAH was responsible for the introduction to the topic. MMB was responsible for the clinical case.

  • Competing interests None declared.

  • Patient consent Obtained.

  • Provenance and peer review Not commissioned; externally peer reviewed.