BMJ Case Reports 2017; doi:10.1136/bcr-2017-220051
  • Unusual association of diseases/symptoms

Livedoid eruption in a patient affected by T-γδ large granular lymphocyte leukaemia

  1. Mauro Alaibac
  1. Unit of Dermatology, University of Padua, Padova, Italy
  1. Correspondence to Professor Mauro Alaibac, mauro.alaibac{at}
  • Accepted 28 August 2017
  • Published 7 September 2017


Livedo is an ischaemic dermopathy characterised by a reddish-blue to violaceous mottling of the skin with a net-like reticular appearance. Livedo has been described in association with several medical conditions including lymphoproliferative disorders. Here, we describe the case of a 60-year-old woman who was presented with asymptomatic and persistent livedoid eruption on her trunk, lower and upper extremities as manifestation of an indolent form of T-γδ large granular lymphocyte leukaemia. To the best of our knowledge, this is the first report describing the association between livedo reticularis and T-γδ large granular lymphocyte leukaemia. It is plausible that a pathogenetic role of the neoplastic process is based on a cytotoxic antiendothelial activity.


  • Contributors GB, GS and IR were involved in the conception of the work, drafting the article, critical revision of the article. AM was involved in the conception of the work, critical revision of the article and final approval of the version to be published.

  • Competing interests None declared.

  • Patient consent Obtained.

  • Provenance and peer review Not commissioned; externally peer reviewed.

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