Article Text
Summary
A 17-year-old female with recently relapsed acute lymphoblastic leukaemia and a treatment course complicated by rhinocerebral mucormycosis infection developed severe peripheral neuropathy during the treatment for mucormycosis infection. This was felt to be a medication side effect. Her peripheral neuropathy was refractory to many well-established treatments, but ultimately responded dramatically and consistently to a novel therapy, topical doxepin cream (5%). This case report is the first published report of the application of topical doxepin cream for treatment of peripheral neuropathy in a paediatric patient.
- Peripheral nerve disease
- Paediatric oncology
- Neurology (drugs and medicines)
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Footnotes
Contributors All the authors (ZD, RB, JMK, DJK) have cared for the patient and contributed to the conception, design, writing and editing of this manuscript. All the authors have reviewed the manuscript and agree to its content for submission.
Competing interests None declared.
Patient consent Consent obtained from guardian.
Provenance and peer review Not commissioned; externally peer reviewed.