BMJ Case Reports 2017; doi:10.1136/bcr-2017-219658

Anorectal involvement in a patient with multiple myeloma

  1. Maria João Bettencourt1
  1. 1 Department of Gastroenterology, Centro Hospitalar de Lisboa Central, Lisbon, Portugal
  2. 2 Department of Hematology, Centro Hospitalar de Lisboa Central, Lisbon, Portugal
  1. Correspondence to Dr Tiago Capela, teixeira.capela{at}
  • Accepted 3 April 2017
  • Published 18 April 2017


Multiple myeloma is a neoplastic proliferation of monoclonal plasma cells. Symptomatic gastrointestinal involvement is uncommon. We report the case of a 45-year-old patient admitted with an anorectal polypoid lesion, which progressed to colonic obstruction. Investigation revealed a secondary plasmacytoma associated with multiple myeloma. We discuss the characteristics of this rare entity with poor prognosis, its clinical implications and treatment options.


  • Contributors PR has produced the report and literature review. TC and ALT assisted in the production of the report and were also involved in the care of the patient. MJB oversaw the creation of the report.

  • Competing interests None declared.

  • Patient consent Consent obtained from Next of kin.

  • Provenance and peer review Not commissioned; externally peer reviewed.

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